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KMID : 0363320110320010068
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Journal of Korean Oriental Internal Medicine
2011 Volume.32 No. 1 p.68 ~ p.74
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The Effect of Jerksukji-san and Tangnisodok-eum on burn
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Lee Dae-Hyun
Han Hyun-Jin
Seo Eui-Seok
Jeong Hyun-Suk
Kang Sei-Young
Jang In-San
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Abstract
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Objectives: The present study was conducted to determine whether Jerksukji-san and Tangnisodok-eum have an effect on treatment of burn.
Methods: 24 male rats were randomly divided into 4 groups. Burns were created by scalding on the skin surface. Immediately after being burned, the rats of group 1 were applied with silver sulfadiazine ointment topically on the burn wound. The rats of group 2 were applied with Jerksukji-san ointment topically and administrated Tangnisodok-eum orally. The rats of group 3 were applied with Jerksukji-san ointment topically. The rats of group 4 were cleaned with saline solution. All treatments were applied twice a day. After 3 and 7 days the inflammatory cellularinfiltration and epidermal gap were measured. Data were analyzed by one-way ANOVA and Kruskal-Wallis test.
Results: The rats of groups 1 and 2 showed a statistically narrow epithelial gap compared with those of groups 3 and 4 on the third and on seventh days (p<0.05). Group 3 showed a statistically narrow epithelial gap compared with group 4 on the third and seventh days (p<0.05). The decrease of inflammatory cellularinfiltration observed in group 2 was bigger than in the other groups (group 2>1>3>4) on the third and seventh days.
Conclusions : These results demonstrate that Tangnisodok-eum and Jerksukji-san ointment are effective to treat burn, and it is necessary for clinical study to better ascertain this method.
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KEYWORD
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burn, Jerksukji-san, Tangnisodok-eum
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